Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut
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چکیده
منابع مشابه
Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut
The pathogenesis of inflammatory bowel disease (IBD) is multifactorial with data suggesting the role of a disturbed interaction between the gut and the intestinal microbiota. A defective mucosal barrier may result in increased intestinal permeability which promotes the exposition to luminal content and triggers an immunological response that promotes intestinal inflammation. IBD patients displa...
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Introduction: Disorders in intestinal permeability have been reported in the pathophysiology of inflammatory bowel diseases (IBD) that may be compensated by complementary therapies through modifying the composition of the intestinal microflora. This study was designed to evaluate the effect of probiotic yogurt on intestinal permeability in patients with IBD. Materials and Methods: In this doubl...
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Inflammatory bowel diseases (IBD) including most important forms; Crohn’s disease (CD) and ulcerative colitis (UC); are chronic diseases affecting the gastrointestinal tract with unclear etiology and pathology. The role of gut microbiota has recently been considered as major a factor, since altered microbiome or "dysbiosis" is a key player in the protracted course of inflammation in IBD. Howeve...
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There is recent renewed interest in the role of the intestine in the pathogenesis of the various arthritides'7. In general, it is postulated that an intestinal microbial constituent or product is absorbed by the intestinal mucosa eliciting an immunological response and tissue damage by simple or induced molecular mimicry"'. The difference between the two mechanisms can best be shown by consider...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2015
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2015/628157